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MRCPUK Endocrinology and Diabetes (Specialty Certificate Examination) : SEND
- Exam Code: SEND
- Exam Name: Endocrinology and Diabetes (Specialty Certificate Examination)
- Q & A: 200 Questions and Answers
About MRCPUK Endocrinology and Diabetes (Specialty Certificate Examination) : SEND Exam
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MRCPUK SEND Exam Syllabus Topics:
| Section | Objectives |
|---|---|
| General Endocrinology | - Integrated Clinical Practice
|
| Thyroid Disorders | - Thyroid Disease
|
| Pituitary and Hypothalamic Disorders | - Pituitary Disease
|
| Diabetes Mellitus | - Management
|
| Calcium and Bone Metabolism | - Parathyroid and Metabolic Bone Disease
|
| Reproductive Endocrinology | - Gonadal Disorders
|
| Adrenal Disorders | - Adrenal Disease
|
MRCPUK Endocrinology and Diabetes (Specialty Certificate Examination) Sample Questions:
Question #1
A 56-year-old man with a 5-year history of type 2 diabetes mellitus was worried about developing a foot ulcer.
Which clinical feature, if present, best predicts the development of a foot ulcer in a patient with diabetes?
- A. absent sensation to a monofilament
- B. vibration perception threshold >25v
- C. history of a previous foot ulcer
- D. inability to perform own foot care
- E. absent foot pulses
Correct Answer: C 🗳️
Question #2
A 26-year-old woman presented acutely with abdominal pain. On examination, her blood pressure was 124/72 mmHg.
Investigations:
24-h urinary dopamine10 000 nmol (<3100)
24-h urinary adrenaline43 nmol (<144)
24-h urinary noradrenaline146 nmol (<570)
CT scan of abdomen3-cm left para-aortic mass
She underwent surgical exploration and removal of the lesion, which proved to be a paraganglioma. One local lymph node, removed at the same time, was also positive for the presence of tumour.
What is the most likely underlying genetic syndrome?
- A. von Hippel-Lindau syndrome
- B. multiple endocrine neoplasia type 2a
- C. Gardner's syndrome
- D. succinate dehydrogenase type B mutation
- E. neurofibromatosis type 1 mutation
Correct Answer: D 🗳️
Question #3
A 25-year-old woman who was 4 months pregnant presented with weight loss of 3 kg over the previous 4 weeks, associated with intermittent palpitations, tremor and feeling of warmth. She was not taking any medication.
On examination, her pulse was 100 beats per minute and regular, and her blood pressure was 130/60 mmHg. A symmetrical non-tender goitre was palpable, with an audible bruit. There was no exophthalmos.
Investigations:
serum thyroid-stimulating hormone<0.1 mU/L (0.4-5.0)
serum free T445.2 pmol/L (10.0-22.0)
serum free T322.8 pmol/L (3.0-7.0)
anti-thyroid stimulating hormone receptor
antibodies40 U/L (<7)
What is the most appropriate treatment?
- A. radioactive iodine
- B. propylthiouracil
- C. propranolol
- D. carbimazole
- E. subtotal thyroidectomy
Correct Answer: D 🗳️
Question #4
A 23-year-old man presented with a history of discomfort with his gender for as long as he could remember. He believed he was transsexual.
What element of further history would most strongly support his self-diagnosis?
- A. a long-standing intense wish to make his body conform to that of the preferred gender
- B. sexual excitement by cross-dressing
- C. seeking medical rationalisation for sexuality through genital surgery
- D. conscious and absolute rejection of his sexual orientation as socially unacceptable
- E. the presence of gender somatic delusions that emerge and strengthen with time
Correct Answer: A 🗳️
Question #5
A 55-year-old woman was referred with a 6-month history of type 2 diabetes mellitus. She was not taking any regular medication. She was a non-smoker. She drank 10 units of alcohol per week. Her general practitioner had arranged for her to see the community dietician as the patient had made significant changes to her diet.
On examination, she was obese with a body mass index of 31.8 kg/m2 (18-25). Her liver was not palpable.
Investigations:
serum ferritin310 ug/L (15-300)
serum total bilirubin16 umol/L (1-22)
serum alanine aminotransferase80 U/L (5-35)
serum aspartate aminotransferase75 U/L (1-31)
serum alkaline phosphatase150 U/L (45-105)
serum gamma glutamyl transferase35 U/L (4-35)
haemoglobin A1c67 mmol/mol (20-42)
serum cholesterol6.2 mmol/L (<5.2)
serum HDL cholesterol0.90 mmol/L (>1.55)
fasting serum triglycerides2.50 mmol/L (0.45-1.69)
What is the most appropriate management of her dyslipidaemia?
- A. fenofibrate
- B. simvastatin
- C. metformin
- D. omega-3-acid ethyl esters
- E. ezetimibe
Correct Answer: B 🗳️
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